Transition Metal-Catalyzed Decarboxylative Allylation and Benzylation Reactions
نویسندگان
چکیده
منابع مشابه
Transition Metal-Catalyzed Decarboxylative Coupling Reactions of Alkynyl Carboxylic Acids
The decarboxylative couplings of alkynyl carboxylic acids are an attractive area of research in organic chemistry, because the structure of aryl alkyne is one of the important building blocks for the synthesis of p-conjugated compounds. The use of alkynyl carboxylic acid as an alkyne source has several advantages in handling and storage. As a catalyst, palladium, copper, nickel, and silver were...
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The Pd-catalyzed direct alkylation of H-phosphinic acids and hypophosphorous acid with allylic/benzylic alcohols has been described previously. Here, the extension of this methodology to H-phosphinate esters is presented. The new reaction appears general, although its scope is narrower than with the acids, and its mechanism is likely different. Various alcohols are examined in their reaction wi...
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Trifluoromethyl-substituted arenes and heteroarenes are widely prevalent in pharmaceuticals and agrochemicals. As a result, the development of practical methods for the formation of aryl–CF3 bonds has become an active field of research. Over the past five years, transition-metal-catalyzed cross-coupling between aryl–X (X = halide, organometallic, or H) and various ‘CF3’ reagents has emerged as ...
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The ruthenium-catalyzed stereospecific decarboxylative allylation of ketone enolates provides access to gamma,delta-unsaturated ketones with good yields and enantio-enrichments.
متن کاملRegiospecific decarboxylative allylation of nitriles.
Palladium-catalyzed decarboxylative alpha-allylation of nitriles readily occurs with use of Pd(2)(dba)(3) and rac-BINAP. This catalyst mixture also allows the highly regiospecific alpha-allylation of nitriles in the presence of much more acidic alpha-protons. Thus, the reported method provides access to compounds that are not readily available via base-mediated allylation chemistries. Lastly, m...
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ژورنال
عنوان ژورنال: Chemical Reviews
سال: 2011
ISSN: 0009-2665,1520-6890
DOI: 10.1021/cr1002744